France – Research and development services and related consultancy services – Projet aRTwin Plateforme de jumeaux numériques hybrides (biophysique et IA multimodale) pour la radiothérapie et l'hadronthérapie

The aRTwin project, co-financed by the European Union (ERDF, Normandy Region programme), aims to build a hybrid digital twin platform, combining biophysical and radiobiological models and multimodal artificial intelligence, for radiotherapy and hadrontherapy (protons and carbon ions; helium ions optionally). The work focuses on research and evaluation; no clinical use is planned as part of the contract. The contract is divided into three lots: lot 1 - data and modelling (multimodal database, biophysical and radiobiological modelling, AI, simulated digital twins coupled with the RayStation planning software), in-house, in hybrid format according to a quarterly on-site presence schedule; lot 2 - preclinical research in hadrontherapy (production or reanalysis of experimental data, existing or produced during the contract, on hypoxia and radioresistance; firm in vitro slice and optional in vivo slice); lot 3 - platform, infrastructure and architecture (architecture, integrative platform, DICOM/FHIR interoperability, MLOps chain), in-house, in hybrid format according to a quarterly on-site presence schedule, without supply of equipment. Health data processing is carried out exclusively in the Centre's premises. The services end at the latest on 30 November 2028, a date that can be extended by a maximum of twelve months. The Centre reserves the right to award similar services to the contract holders (Article R. 2122-7 of the Public Procurement Code).