Italy – Research and development services and related consultancy services – Novel strategy for allergenicity risk assessment of proteins in regulated food and feed products

The aim of this call is to seek support for the development of a novel strategy for allergenicity risk assessment (RA) of proteins in food and feed. For both clinically-relevant cross-reactivity and de novo sensitisation, the project foresees the development of open source in silico prediction/appraisal tools to be validated with experimental data; assessment of future prospects for in silico tools; estimation of thresholds of allergological concern, and the development of a systematic tiered approach with a decision-making framework. This novel strategy will enhance the reliability and speed of allergenicity RA and support process simplification and harmonisation, ultimately enabling better-informed risk management decision-making.